Book DetailAuthor/Editor(s): William F. Rosenberger, John M. Lachin
Publication Date: November 23, 2015
Size: 2.26 MB
Book DescriptionFeaturing a unique combination ofthe applied aspects of randomization in clinical trials with a nonparametric approach to inference, Randomization in Clinical Trials: Theory and Practice, Second Edition is the go-to guide for biostatisticians and pharmaceutical industry statisticians. A consolidated review of the field, the Second Edition focuses on computation of randomized tests rather than the asymptotic theory of randomized tests.
Randomization in Clinical Trials: Theory and Practice, Second Edition features:
- A discussion on current philosophies, controversies, and new developments in the increasingly important role of randomization techniques in clinical trials
- A new chapter on covariate-adjusted response-adaptive randomization, including minimization techniques and inference for covariate-adaptive randomization
- New developments in restricted randomization and an increased focus on computation of randomization tests as opposed to the asymptotic theory of randomization tests
- Many problem sets, theoretical exercises, and short computer simulations using SAS® to facilitate classroom teaching, to simplify the mathematics, and to ease understanding
Randomization in Clinical Trials: Theory and Practice, Second Edition is an excellent reference for researchers as well as applied statisticians and biostatisticians. The Second Edition is also an ideal textbook for upper-undergraduate and graduate-level courses in biostatistics and applied statistics.
All medical statisticians involved in clinical trials should read this book….
--Controlled Clinical Trials